Efforts are underway to restore the chestnut tree to its place in American deciduous forests. The American Chestnut Foundation is conducting research to develop blight resistant strains. Asian chestnut trees are resistant to blight, so a back-cross breeding program is underway to find a suitable variety to reintroduce. Breeders want to retain as much American genome as possible while obtaining blight resistance from Asian genes. Asian trees look different and grow differently in the forest.
The blight fungus lives in the tree's cambium where it spreads and girds the tree killing it. A resistant tree forms a canker which stops the fungus from spreading. The University of Virginia has been conducting breeding research for fifty years and is working with the Foundation to establish a breeding colony from which seedlings can be planted in Virginia's forests. This type of breeding program is important for other species such as ash and white pine, both of which are suffering from disease.